Here's How To Cure That Terrible Ozempic Headache
That Ozempic Headache Is Real — Here’s How To Beat It
Headaches are a common and frustrating side effect some people experience while taking the popular weight loss drug Ozempic, but the medication itself may not be to blame. According to fitness and nutrition expert Dr. Chris Mohr and board-certified physician Dr. Raj Dasgupta, these headaches are typically a result of how the drug interacts with your body, not a direct effect of the medication.
During an interview with Woman’s World published on April 29, Dr. Mohr explained that Ozempic works by lowering blood sugar levels and suppressing appetite. These changes, especially if you are not eating enough, can trigger those unwelcome headaches.
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Ozempic, the brand name for semaglutide, works by mimicking a natural hormone in the body called GLP-1 (glucagon-like peptide-1), which is released after eating. Ozempic helps lower blood sugar levels by increasing insulin production when needed and reducing the amount of sugar released by the liver. Dr. Mohr explained that this sugar reduction process can lead to “fluctuations,” which is typically the pesky culprit responsible for those terrible headaches.
“Headaches from Ozempic may come from the way it interacts with your body’s GLP-1 receptors. This influence on glucose processing can lead to sugar level fluctuations, commonly associated with headaches,” he explained. “Ozempic can also bring about side effects like dehydration or changes in digestion, contributing to headaches.”
Eating less and drinking less can also cause a headache to occur.
Secondly, Ozempic enhances feelings of fullness by slowing down digestion and influencing the brain’s hunger signals, which helps reduce appetite and curb overeating. However, eating less can at times cause a painful headache to occur.
Dr. Dasgupta added that if you aren’t eating or drinking enough nourishing fluids, your “blood sugar can dip and dehydration can sneak up on you,” causing that side-splitting headache to develop.
“Once again, both are common triggers for headaches, especially when your body’s still adjusting to the medication,” he said.
To help relieve these symptoms, Dr. Raj suggests that something as simple as staying hydrated and having a healthy snack can often make a difference.
“Staying hydrated and eating small healthy snacks throughout the day can help keep headaches at bay. Since GLP-1 RAs such as Ozempic can disorient your hunger cues, drinking water often, checking your blood sugar, and having healthy snacks can help keep blood sugar and hydration steady, which helps reduce the chance of a headache,” he advised.
He also explained that certain medications, such as pain relievers (Ibuprofen) and anti-inflammatory drugs (NSAIDs) may interact negatively with Ozempic, so it’s best to avoid them while taking the weight loss drug.
“Acetaminophen is typically a safer alternative for pain relief but, again, always talk with your own doctor about what may be best for you,” Dr. Dasgupta added.
If the headaches persist or worsen, it’s important to consult your doctor. They may recommend adjusting your dosage or exploring a different weight loss medication that’s better suited to your needs.
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