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Gettyimages.com/Sad black couple ignoring each other while sitting back to back on a window sill.

Trust issues, communication issues, commitment issues…these are all struggles couples can face. With the right counseling and by doing the work, they can overcome them. These are usually the types of problems depicted in romantic comedies, dramas, or just about any program about love. But what you don’t often see or hear about is a problem that isn’t really within a couple’s control: a chronic disease. Life can be funny sometimes, and it might give you a partner who is just perfect for you—you couldn’t possibly be more compatible or get along better—there’s just one thing: he has a chronic condition. Your interpersonal relationship is almost flawless but then you get thrown this curveball of a chronic condition. It’s going to affect your relationship if your relationship gets serious. Here is what it’s like dating someone with a chronic condition.

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Many trips are cut short

Get ready to cut a lot of trips short. When symptoms flare up, your partner may need to go to the hospital, go home to see his doctor, or just lay in bed in the hotel room for several days. Either way, many vacations will be cut short, without much warning.

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Travel can be stressful

Traveling can be very stressful. It’s so important that all necessary prescriptions are filled and picked up in time for the trip. You need to know about hospitals and pharmacies near the hotel, in case of an emergency. Your partner may have very specific dietary needs that you need to work out with every hotel, host, and airline before traveling.

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The false hope of good days

You’ll have bouts of good days that last for weeks or even months—these bouts give you false hope that maybe your partner is cured. But chronic means chronic, and it can be devastating to get your hopes up like that only to have symptoms come back (which they will).